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揭示皮肤的秘密生活——与微生物组同行,永不孤单。

Revealing the secret life of skin - with the microbiome you never walk alone.

机构信息

DSM Nutritional Products, Personal care, Wurmisweg 576, CH-4303, Kaiseraugst, Switzerland.

Faculty of Medical and Life Sciences, Institute of Precision Medicine, Furtwangen University, Jakob-Kienzle-Str. 17, Villingen-Schwenningen, 78054, Germany.

出版信息

Int J Cosmet Sci. 2020 Apr;42(2):116-126. doi: 10.1111/ics.12594. Epub 2019 Dec 25.

Abstract

The human skin microbiome has recently become a focus for both the dermatological and cosmetic fields. Understanding the skin microbiota, that is the collection of vital microorganisms living on our skin, and how to maintain its delicate balance is an essential step to gain insight into the mechanisms responsible for healthy skin and its appearance. Imbalances in the skin microbiota composition (dysbiosis) are associated with several skin conditions, either pathological such as eczema, acne, allergies or dandruff or non-pathological such as sensitive skin, irritated skin or dry skin. Therefore, the development of approaches which preserve or restore the natural, individual balance of the microbiota represents a novel target not only for dermatologists but also for skincare applications. This review gives an overview on the current knowledge on the skin microbiome, the currently available sampling and analysis techniques as well as a description of current approaches undertaken in the skincare segment to help restoring and balancing the structure and functionality of the skin microbiota.

摘要

人类皮肤微生物组最近成为皮肤科和化妆品领域的关注焦点。了解皮肤微生物群,即生活在我们皮肤上的重要微生物的集合,以及如何维持其微妙的平衡,是深入了解健康皮肤及其外观的机制的重要步骤。皮肤微生物群组成的失衡(失调)与几种皮肤状况有关,无论是病理性的,如湿疹、痤疮、过敏或头皮屑,还是非病理性的,如敏感皮肤、刺激性皮肤或干燥皮肤。因此,开发保留或恢复微生物群自然个体平衡的方法不仅是皮肤科医生的目标,也是护肤品应用的目标。这篇综述概述了皮肤微生物组的最新知识、目前可用的采样和分析技术,以及护肤品领域为帮助恢复和平衡皮肤微生物组的结构和功能而采取的当前方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/7155096/32ae08ed49e3/ICS-42-116-g001.jpg

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