[Effect of biogenic amines on glycogen degradation in isolated rat hepatocytes].
作者信息
Popova I A, Presnova V N, Lavrenova T P
出版信息
Vopr Med Khim. 1992 Mar-Apr;38(2):30-3.
PMID:1413626
Abstract
Serotonin and tyramine affected dissimilarly the enzyme activity involved in degradation of glycogen in isolated rat hepatocytes. Serotonin inhibited hydrolytic enzymes acid alpha-glucosidase, alpha-amylase and amylo-1,6-glucosidase but activated phosphorylase inducing a decrease of glycogen content in cells. Tyramine inhibited acid alpha-glucosidase and amylo-1,6-glucosidase, did not affect the alpha-amylase and phosphorylase activities and increased content of glycogen in cells. Tyramine may be used as stimulator of glycogen accumulation in liver cells.
摘要
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