Turnlund J R, Betschart A A, Liebman M, Kretsch M J, Sauberlich H E
Western Human Nutrition Research Center, USDA/ARS, Presidio of San Francisco, CA 94129.
Am J Clin Nutr. 1992 Nov;56(5):905-10. doi: 10.1093/ajcn/56.5.905.
An 84-98-d study was conducted in young women to determine the effect of vitamin B-6-deficient diets on calcium and magnesium metabolism. A vitamin B-6-deficient formula diet fed initially was followed by either animal- or plant-source protein food diets containing four increasing amounts of vitamin B-6. Calcium balance was negative during vitamin B-6 depletion. Serum calcium was higher and calcium balance negative with the plant protein diets. Magnesium balance was negative during vitamin B-6 depletion due to increased urinary magnesium excretion. Urinary calcium decreased during vitamin B-6 depletion and increased as dietary vitamin B-6 increased. Urinary oxalate was significantly higher at the end than at the beginning of vitamin B-6 depletion and was higher with plant than animal protein diets. The results suggest that vitamin B-6 depletion may alter calcium and magnesium metabolism and that dietary components associated with the protein source may influence calcium retention.
在年轻女性中进行了一项为期84 - 98天的研究，以确定缺乏维生素B - 6的饮食对钙和镁代谢的影响。最初喂食缺乏维生素B - 6的配方饮食，随后是含有四种逐渐增加量维生素B - 6的动物或植物来源蛋白质食物饮食。在维生素B - 6缺乏期间钙平衡为负。植物蛋白饮食时血清钙较高且钙平衡为负。由于尿镁排泄增加，在维生素B - 6缺乏期间镁平衡为负。在维生素B - 6缺乏期间尿钙减少，随着饮食中维生素B - 6增加而增加。尿草酸盐在维生素B - 6缺乏结束时显著高于开始时，并且植物蛋白饮食时比动物蛋白饮食时更高。结果表明，维生素B - 6缺乏可能会改变钙和镁的代谢，并且与蛋白质来源相关的饮食成分可能会影响钙的潴留。
