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椎间盘间隙感染:年轻人的另一种下背部综合征。

Intervertebral disc space infection: another low back syndrome of the young.

作者信息

Ettinger W H, Arnett F C, Stevens M B

出版信息

Johns Hopkins Med J. 1977 Jul;141(1):23-7.

PMID:141538
Abstract

Pyogenic disc space infection is a rare and unappreciated cause of low back pain. Reported herein is a young man with chronic low back pain and the HLA-B27 antigen which initially led to the diagnosis of ankylosing spondylitis. However, serial lumbar radiographs and bone scan established an inflammatory lesion involving the L2-L3 intervertebral disc space, and persistently normal sacroiliac joints. A needle biopsy and culture of the disc space yielded Staphylococuss aureus. Treatment with antibiotics, bed rest and back bracing resulted in a complete resolution of symptoms and healing of the vertebral lesion. It is the purpose of this report to review the clinical, laboratory and radiographic features of intervertebral disc space infection as well as pitfalls in its diagnosis.

摘要

化脓性椎间盘间隙感染是导致腰痛的一种罕见且易被忽视的病因。本文报告了一名患有慢性腰痛且携带HLA - B27抗原的年轻男性,最初诊断为强直性脊柱炎。然而,系列腰椎X线片和骨扫描显示L2 - L3椎间盘间隙存在炎性病变,而骶髂关节始终正常。椎间盘间隙穿刺活检及培养发现金黄色葡萄球菌。经抗生素治疗、卧床休息和背部支具固定后,症状完全缓解,椎体病变愈合。本报告旨在回顾椎间盘间隙感染的临床、实验室及影像学特征以及诊断中的陷阱。

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Intervertebral disc space infection: another low back syndrome of the young.椎间盘间隙感染:年轻人的另一种下背部综合征。
Johns Hopkins Med J. 1977 Jul;141(1):23-7.
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The in vivo biological effects of intradiscal recombinant human bone morphogenetic protein-2 on the injured intervertebral disc: an animal experiment.椎间盘内注射重组人骨形态发生蛋白-2对损伤椎间盘的体内生物学效应:一项动物实验。
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Eur Spine J. 1992 Jun;1(1):25-8. doi: 10.1007/BF00302138.