Tohya K, Kimura M
Department of Anatomy, Kansai Shinkyu College, Kansai Academy of Medical Sience, Osaka, Japan.
Anat Embryol (Berl). 1992 Sep;186(4):335-40. doi: 10.1007/BF00185982.
An ultrastructural study was made of the postnatal development of the tonsillar crypt epithelium in the musk shrew, Suncus murinus. On day 3 after birth, a particular kind of large lymphoid cell was first seen to move through the basement membrane into the epithelium. The next migration was that of lymphocytes, which passed through holes in the basement membrane. On days 5 to 7, the lymphocytes formed clusters, and pale epithelial cells of low electron density appeared. The cell clusters and pale epithelial cells fused on day 10. By day 14, these epithelial cells extended cytoplasmic projections to the surface of the epithelium, which had many heterophagic vacuoles and some microvilli-like structures. These findings suggest that the lymphoepithelial relationship is important for the organization of the immunological microenvironment in tonsillar crypt epithelium of the neonatal musk shrew.
对臭鼩（Suncus murinus）扁桃体隐窝上皮的出生后发育进行了超微结构研究。出生后第3天，首次观察到一种特殊的大淋巴细胞穿过基底膜进入上皮。接下来迁移的是淋巴细胞，它们穿过基底膜上的孔。在第5至7天，淋巴细胞形成簇，出现了低电子密度的浅色上皮细胞。细胞簇和浅色上皮细胞在第10天融合。到第14天，这些上皮细胞向上皮表面伸出细胞质突起，上皮表面有许多异噬泡和一些微绒毛样结构。这些发现表明，淋巴上皮关系对于新生臭鼩扁桃体隐窝上皮免疫微环境的组织很重要。
