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饮食诱导的大鼠肠道果糖吸收适应性变化

Diet-induced adaptation of intestinal fructose absorption in the rat.

作者信息

Vrána A, Fábry P, Kazdová L

出版信息

Physiol Bohemoslov. 1977;26(3):225-34.

PMID:141676
Abstract

The effect of dietary sucrose, fructose and glucose on the intestinal absorption of fructose and glucose was investigated in adult rats in vivo: Glucose absorption was not affected by the type of dietary carbohydrate, while the absorption of fructose was increased by the ingestion of the sucrose or fructose diet, as compared with the glucose diet. An almost maximal increase of fructose absorption was already observed when the quarter of the total dietary carbohydrates was replaced by fructose. Faecal fructose elimination declined during the feeding experiment. The enhanced intestinal absorption of the fructose load in rats fed the fructose diet was manifested by higher concentrations of fructose, but also of glucose and lactate in the hepatic portal blood.

摘要

在成年大鼠体内研究了膳食蔗糖、果糖和葡萄糖对果糖和葡萄糖肠道吸收的影响:葡萄糖的吸收不受膳食碳水化合物类型的影响,而与葡萄糖饮食相比,摄入蔗糖或果糖饮食可增加果糖的吸收。当总膳食碳水化合物的四分之一被果糖替代时,就已观察到果糖吸收几乎达到最大程度的增加。在喂养实验期间,粪便中果糖的排出量下降。喂食果糖饮食的大鼠对果糖负荷的肠道吸收增强,表现为肝门静脉血中果糖、葡萄糖和乳酸的浓度升高。

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