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脊髓损伤中的冠状动脉风险:多变量方法后的评估

Coronary risk in spinal cord injury: assessment following a multivariate approach.

作者信息

Cardús D, Ribas-Cardús F, McTaggart W G

机构信息

Baylor College of Medicine, Department of Physical Medicine and Rehabilitation, Houston, TX.

出版信息

Arch Phys Med Rehabil. 1992 Oct;73(10):930-3.

PMID:1417469
Abstract

A group of 96 men with spinal cord injury was studied to find out if patients with spinal cord injury were at an increased risk of coronary heart disease. A multivariate approach based on data produced by the Framingham study was used to estimate the probability of developing coronary artery disease within six years. Data obtained from the 96 patients were compared with data obtained from 96 nontrained, able-bodied men matched according to age. The results of this study suggest that patients with spinal cord injury show a risk of coronary artery disease similar to that estimated in non-trained, age-matched, able-bodied individuals. The risk increases with age, but it is of the same order as that found in the normal population and does not appear to be related to the duration of the disease. The results are inconclusive in regard to the level of the lesion as an independent factor of risk.

摘要

对一组96名脊髓损伤男性进行了研究,以确定脊髓损伤患者患冠心病的风险是否增加。采用基于弗雷明汉研究数据的多变量方法来估计六年内患冠状动脉疾病的概率。将96名患者的数据与96名根据年龄匹配的未受过训练的健全男性的数据进行比较。这项研究的结果表明,脊髓损伤患者患冠状动脉疾病的风险与未受过训练、年龄匹配的健全个体估计的风险相似。风险随年龄增加,但与正常人群中发现的风险处于同一水平,并且似乎与疾病持续时间无关。关于损伤水平作为独立风险因素,结果尚无定论。

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