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脊髓损伤中的血脂谱

Lipid profiles in spinal cord injury.

作者信息

Cardús D, Ribas-Cardús F, McTaggart W G

机构信息

Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas 77030-3405.

出版信息

Paraplegia. 1992 Nov;30(11):775-82. doi: 10.1038/sc.1992.149.

DOI:10.1038/sc.1992.149
PMID:1484728
Abstract

Measurement of blood levels of total cholesterol and lipoproteins (HDL and LDL) were conducted on 96 men with spinal cord injury, 46 paraplegics and 50 quadriplegics. All these patients were studied in the stabilized phase of the disease as a follow up to the rehabilitation process. The study was designed to compare results with a normal, able bodied population and to investigate if any abnormal finding could be related to the age at onset of the spinal cord injury, the duration of the disease or the level of the lesion. Compared to the normal, able bodied population, this study indicates that patients with a spinal cord injury do not have higher levels of cholesterol or LDL, nor lower levels of HDL. Levels of total cholesterol increase with aging, as in the normal population, but have no relation to the duration of the disease or the level of the lesion. Blood levels of HDL and LDL do not seem to be related either to the duration of the disease or to the level of the lesion.

摘要

对96名脊髓损伤男性患者进行了总胆固醇和脂蛋白(高密度脂蛋白和低密度脂蛋白)血液水平的测量,其中46名为截瘫患者,50名为四肢瘫痪患者。所有这些患者均在疾病稳定期进行研究,作为康复过程的随访。该研究旨在将结果与正常健康人群进行比较,并调查是否有任何异常发现与脊髓损伤的发病年龄、疾病持续时间或损伤水平有关。与正常健康人群相比,本研究表明脊髓损伤患者的胆固醇或低密度脂蛋白水平并不更高,高密度脂蛋白水平也不更低。总胆固醇水平与正常人群一样,随年龄增长而升高,但与疾病持续时间或损伤水平无关。高密度脂蛋白和低密度脂蛋白的血液水平似乎也与疾病持续时间或损伤水平无关。

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