Weeke E R
Rhinol Suppl. 1992 Sep;13:5-12.
The one-year-prevalence rate of bronchial asthma in children varies from 1-3%, when investigated in general practice, to 5-7% in population studies. The prevalence rate is highest in young boys. Eighty percent of the asthmatic children are allergic, house-dust-mite allergy being the most common allergy. The one-year-prevalence rate of rhinitis is 5-10% in general practice, and 10-12% in population studies. Again, the prevalence rate is highest in young boys. About 90% of children with rhinitis symptoms are allergic, with pollen allergy as the most common allergy. Risk factors for developing allergic diseases are many. The predisposition is probably the most prevailing risk factor. Period of birth, sex, race, diet, the presence of other allergic diseases, tobacco smoking, pollution, and allergens in the environment, all these factors alone or in combination almost double the risk. There is no doubt that both asthma and hay-fever prevalences have steadily increased within the last 50 years. Also, admissions to hospitals for childhood asthma have continued to increase, while the mortality of asthma in children has not risen statistically. This increase is in contrast to the effective medication available for both asthma and allergic rhinitis, and to the number of preventive factors known to us today. The time has come to try to change it at all costs. The outcome of allergic rhinitis and asthma shows that only 10% are cured, 50% ameliorate, 30% remain unchanged, and 10% deteriorate. Factors determining the outcome are age, immunotherapy, sex, mother's age at childbirth, infections, other allergic diseases, and signs and symptoms of food allergy.(ABSTRACT TRUNCATED AT 250 WORDS)
在全科医疗调查中,儿童支气管哮喘的一年患病率为1%-3%,而在人群研究中则为5%-7%。患病率在幼年男孩中最高。80%的哮喘儿童有过敏反应,其中屋尘螨过敏最为常见。在全科医疗中,鼻炎的一年患病率为5%-10%,在人群研究中为10%-12%。同样,患病率在幼年男孩中最高。约90%有鼻炎症状的儿童有过敏反应,其中花粉过敏最为常见。引发过敏性疾病的风险因素众多。易感性可能是最主要的风险因素。出生时期、性别、种族、饮食、是否患有其他过敏性疾病、吸烟、污染以及环境中的过敏原,所有这些因素单独或共同作用几乎会使风险翻倍。毫无疑问,在过去50年里,哮喘和花粉热的患病率都在稳步上升。此外,儿童哮喘的住院人数持续增加,而儿童哮喘的死亡率在统计学上并未上升。这种增长与现有的哮喘和过敏性鼻炎有效药物以及我们如今已知的预防因素数量形成了对比。现在是不惜一切代价尝试改变这种情况的时候了。过敏性鼻炎和哮喘的治疗结果显示,仅10%被治愈,50%症状改善,30%无变化,10%病情恶化。决定治疗结果的因素包括年龄、免疫疗法、性别、母亲分娩时的年龄、感染、其他过敏性疾病以及食物过敏的体征和症状。(摘要截选至250词)