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纤连蛋白在正常人皮肤初始淋巴管和血管中的定位:一项免疫电子显微镜研究。

Localization of fibronectin in the initial lymphatics and blood vessels of normal human skin: an immunoelectron microscopic investigation.

作者信息

Lubach D, Nissen S, Marghescu S

机构信息

Department of Dermatology (Hautklinik Linden) Medizinische Hochschule Hannover, Germany.

出版信息

J Dermatol Sci. 1992 Sep;4(2):63-8. doi: 10.1016/0923-1811(92)90060-o.

DOI:10.1016/0923-1811(92)90060-o
PMID:1419980
Abstract

The initial lymphatics of the human skin do not possess a basal lamina, but a subendothelial fibrous network, of which we do not know the biochemical and immunohistological composition. We investigated the wall of blood vessels and initial lymphatics in normal human skin for the presence of fibronectin by immunoelectron microscopy. We found discontinuous linear subendothelial diaminobenzidine (DAB) reaction products in both blood vessels and lymphatics. In addition fibronectin could be found at the anchoring fibrils of the initial lymphatics.

摘要

人类皮肤的初始淋巴管没有基底膜,而是具有内皮细胞下纤维网络,其生化和免疫组织学组成尚不清楚。我们通过免疫电子显微镜研究了正常人皮肤中血管壁和初始淋巴管中纤连蛋白的存在情况。我们发现血管和淋巴管的内皮细胞下二氨基联苯胺(DAB)反应产物均不连续且呈线性。此外,在初始淋巴管的锚定原纤维处也能发现纤连蛋白。

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