Homology-derived three-dimensional structure prediction of Candida cylindracea lipase.
作者信息
Longhi S, Lotti M, Fusetti F, Pizzi E, Tramontano A, Alberghina L
机构信息
Dipartimento di Fisiologia e Biochimica Generali, Università degli Studi di Milano, Italy.
出版信息
Biochim Biophys Acta. 1992 Nov 11;1165(1):129-33. doi: 10.1016/0005-2760(92)90084-9.
PMID:1420342
Abstract
We propose a structural model of Candida cylindracea lipase (CCL) based on the reported X-ray structure of the highly homologous Geotrichum candidum lipase (GCL). The network of interactions around the active site, the salt and disulfide bridge pattern is conserved in the proposed structure. Functional, structural and evolutionary aspects of the peculiar usage of CTG codons by C. cylindracea ATCC 14830 are discussed.
摘要
Zotero 插件