Biotin in man's nutrition and therapy -- a review.

The literature on biotin in human nutrition and therapy has been reviewed. The influence of the diet on biotin excretion and the intestinal synthesis of biotin is discussed. Biotin deficiency symptoms are occasionally seen, especially in infants where the deficiency is manifested as seborrhoeic dermatitis. Nevertheless, low urinary excretion and low circulating biotin levels can be found in certain sections of the population.