放线菌素D：对大鼠肝脏匀浆的作用与其对RNA合成的作用无关。
ACTINOMYCIN D: AN EFFECT ON RAT LIVER HOMOGENATES UNRELATED TO ITS ACTION ON RNA SYNTHESIS.
作者信息
REVEL M, HIATT H H, REVEL J P
出版信息
Science. 1964 Dec 4;146(3649):1311-3. doi: 10.1126/science.146.3649.1311.
Abstract
Liver homogenates prepared from rats injected with high doses of actinomycin D show a decrease in polyribosome content and in amino acid incorporation. These effects are not observed in rat liver not subjected to homogenization and are independent of the inhibition of RNA synthesis caused by the antibiotic.
摘要
用高剂量放线菌素D注射的大鼠制备的肝匀浆显示多核糖体含量和氨基酸掺入量减少。在未进行匀浆处理的大鼠肝脏中未观察到这些效应，并且这些效应与抗生素引起的RNA合成抑制无关。
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