Reĭkhardt B A, Beliavtseva L M, Kulikova O G
Biull Eksp Biol Med. 1992 May;113(5):506-8.
Incorporation of 3H-leucine into proteins of rat brain cell structures during application of antifeins (compounds of alternative action on memory processes) has been studied. No correlation was observed between changes in protein synthesis in nuclei, mitochondria, components of endoplasmic reticulum and memory effects of ethyl-, allyl- and propylnorantifeins. Only M1 and M2-demethylated structural analogs of ethylnorantifeins (exerting the most effective action on RNA synthesis and retention of conditional reflexes) enhanced the synaptosomal protein synthesis.
在应用抗兴奋药（对记忆过程具有交替作用的化合物）期间，研究了将³H-亮氨酸掺入大鼠脑细胞结构蛋白质中的情况。未观察到细胞核、线粒体、内质网成分中蛋白质合成的变化与乙基、烯丙基和丙基去甲抗兴奋药的记忆效应之间存在相关性。只有乙基去甲抗兴奋药的M1和M2去甲基化结构类似物（对RNA合成和条件反射的保留发挥最有效作用）增强了突触体蛋白质合成。
