Trinus F P, Kurskiĭ M D, Gubskiĭ Iu I, Bukhtiarova T A
Biull Eksp Biol Med. 1992 May;113(5):508-9.
In the mice hot-plate test we have compared analgesic effect of calcium channel blockers and new non-narcotic analgesic antiinflammatory agent PV-107: verapamil > fenigidin > PV-107. Simultaneously we have shown strong correlation (r - 0.82) between analgesic effect and 45Ca2+ efflux of cardiac membrane in depolarizing media in vitro.
