Valiullin V V, Dzamukov R A, Islamov R R, Prokhorenko E L, Poletaev G I
Biull Eksp Biol Med. 1992 Jul;114(7):93-5.
After transferrin injection to the slow m. soleus of guinea pig no immunohistochemical changes in myosin composition with monoclonal antibodies (AB) against fast myosin heavy chain (HCf) have been found. All muscles fibers in intact and experimental animals were identified as slow ones (type I of muscle fibers). After colchicine treatment of nerve trunk innervating slow muscle, some muscle fibers reacting with monoclonal AB against myosin HCf have been found. However, after colchicine treatment of nerve trunk and transferrin injection also some muscle fibers in slow muscle reacting with monoclonal AB against myosin HCf have been found. In appears that transferrin probably can not be the factor of neurotrophic control for myosin composition in skeletal muscle.
给豚鼠比目鱼慢肌注射转铁蛋白后，未发现用抗快肌肌球蛋白重链（HCf）的单克隆抗体（AB）检测到的肌球蛋白组成有免疫组织化学变化。完整动物和实验动物的所有肌纤维均被鉴定为慢肌纤维（I型肌纤维）。用秋水仙碱处理支配慢肌的神经干后，发现一些肌纤维与抗肌球蛋白HCf的单克隆AB发生反应。然而，在用秋水仙碱处理神经干并注射转铁蛋白后，慢肌中也发现了一些与抗肌球蛋白HCf的单克隆AB发生反应的肌纤维。看来转铁蛋白可能不是骨骼肌中肌球蛋白组成的神经营养控制因子。
