KIDD D J
Can Med Assoc J. 1964 Oct 31;91(18):941-5.
Current achievements in environments at pressures higher than atmospheric are reviewed, ranging from the uses of hyperbaric oxygen for treatment to the concept of residence at high pressure for extended Continental Shelf exploration and very deep caisson work.A case is made for the use of high oxygen pressures in the treatment of hypoxias of acute onset, of certain infections, and as an adjunct to radiotherapy. Achievement of the desired high tissue tensions of oxygen while avoiding toxicity requires careful choice of both pressure and duration of exposure.Man has successfully dived to 1000 feet in the sea, and has remained for weeks at high pressures. Adequate prophylactic decompression remains a major problem, since current recompression procedures are to a large extent empirically derived. There are grounds for expecting improved prophylactic and therapeutic procedures when present studies are completed.
本文综述了高于常压环境下的当前研究成果，内容涵盖从高压氧治疗的应用到为进行大陆架深度勘探和超深沉箱作业而进行高压居住的概念。文中提出了在治疗急性缺氧、某些感染以及作为放疗辅助手段时使用高氧压的理由。在避免毒性的同时实现所需的高组织氧张力，需要仔细选择压力和暴露时间。人类已成功潜入海中1000英尺深处，并在高压环境下停留数周。充分的预防性减压仍然是一个主要问题，因为目前的再压缩程序在很大程度上是基于经验得出的。有理由期待在当前研究完成后，预防性和治疗性程序会得到改进。
