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婴儿的气体代谢:镇静和清醒的影响。

GASEOUS METABOLISM IN THE INFANT: THE EFFECT OF SEDATION AND OF WAKEFULNESS.

作者信息

LEES M H

出版信息

Can Med Assoc J. 1964 Oct 31;91(18):955-60.

Abstract

Accurate oxygen consumption figures are desirable in quantitation of blood flow and shunts in infants with heart disease. Figures derived from normal infants fail to take into account effects of sedation or wakefulness.Oxygen consumption and ventilatory data were obtained in nine infants in natural sleep, in sedated sleep and in wakefulness. In sedated sleep oxygen consumption fell by a mean of 22% below the figure for natural sleep, and arterial carbondioxide tension rose by a mean of 7.04 mm. Hg. Infants who were awake but quiet (less than five limb movements per minute) showed an average increase in oxygen consumption of 28% as compared with data obtained during natural sleep.Direct measurement of oxygen consumption of infants is desirable in every instance where flow calculations are to be derived from the Fick equation. When the demands of urgency make this impractical, assumed oxygen consumptions should take into account the factor of sleep or wakefulness.

摘要

准确的耗氧量数据对于定量患有心脏病婴儿的血流量和分流情况很有必要。从正常婴儿得出的数据未能考虑到镇静或清醒的影响。在九名婴儿处于自然睡眠、镇静睡眠和清醒状态时获取了耗氧量和通气数据。在镇静睡眠状态下,耗氧量平均比自然睡眠状态下的数值降低了22%,动脉二氧化碳分压平均升高了7.04毫米汞柱。清醒但安静(每分钟肢体运动少于五次)的婴儿与自然睡眠期间获得的数据相比,耗氧量平均增加了28%。在每一个要根据菲克方程得出流量计算结果的情况下,直接测量婴儿的耗氧量都是可取的。当紧急情况使得这样做不切实际时,假定的耗氧量应考虑睡眠或清醒因素。

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