Bloch-Michel E, Audoin-Berault J, Diebold J, Herman D, Dry J, Campinchi R
Arch Ophtalmol (Paris). 1977;37(2):89-100.
The relatively simple and precise technique of direct immunofluorescence on a tissue section enables the study and enumeration of all types of plasma cells including mastocytes (stained with acridine orange) in normal conjunctiva (5 cases), chronic non-allergic conjunctivitis (5 cases), allergic conjunctivitis of the educt (11 cases) and vernal conjunctivitis (11 cases). There is evidence of elevation of IgE plasma cells in type I allergic conjunctivitis where they are twice as raised as in non-allergic cases in adult forms, and three times more elevated in vernal conjunctivitis. There was no correlation between the number of IgE plasma cells in the tissues and IgE level in sera. Thus in air-borne conjunctival allergies local hypersensitivity seems to be the predominant, even exclusive, feature.
在组织切片上进行直接免疫荧光这种相对简单且精确的技术，能够对正常结膜（5例）、慢性非过敏性结膜炎（5例）、特应性过敏性结膜炎（11例）和春季结膜炎（11例）中包括肥大细胞（用吖啶橙染色）在内的所有类型浆细胞进行研究和计数。有证据表明，在Ⅰ型过敏性结膜炎中IgE浆细胞增多，在成人型中其数量是非过敏性病例的两倍，在春季结膜炎中则高出三倍。组织中IgE浆细胞的数量与血清中IgE水平之间没有相关性。因此，在空气传播性结膜过敏中，局部超敏反应似乎是主要的，甚至是唯一的特征。
