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[高压氧对代偿性心肌肥大状态下心脏的若干功能和形态学特性及儿茶酚胺代谢的影响]

[Effect of hyperbaric oxygenation on several functional and morphologic properties of the heart and catecholamine metabolism in the presence of compensatory myocardial hypertrophy].

作者信息

Efuni S N, Demurov E A, Koloskov Iu B, Tepliakov V G, Khitrov N K

出版信息

Biull Eksp Biol Med. 1977 Jul;84(7):19-22.

PMID:142532
Abstract

Rabbits subjected to hyperbaric oxygenation (HBO) for one month following ascending aorta stenosis developed less distinct hypertrophy and signs of myocardial dystrophy with a more distinct enhancement of the left ventricular contractility than animals with aortic stenosis kept under normal pressure. In rabbits with heart hypertrophy developing under HBO the increasing adaptive capacity of the myocardium was accompanied by an elevation in functional reserve of the sympathetic regulation apparatus. Apparently HBO aided the development of the optimum cardiac adaptation to a high afterload.

摘要

升主动脉狭窄后接受高压氧治疗(HBO)一个月的兔子,与处于常压下的主动脉狭窄动物相比,其心肌肥厚不太明显,心肌营养不良的体征也较轻,而左心室收缩力增强更为明显。在HBO条件下发生心脏肥大的兔子中,心肌适应性能力的增强伴随着交感神经调节装置功能储备的提高。显然,HBO有助于心脏对高后负荷形成最佳适应性。

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