Postnov Iu V, Orlov S N, Shevchenko A S
Biull Eksp Biol Med. 1977 Jul;84(7):41-4.
A greater amount of calcium is removed with the aid of EDTA from the erythrocyte membranes of patients with hypertensive disease than from erythrocytes of persons with a normal arterial blood pressure. When isotonic MgCl2 was used the amount of calcium removed from the erythrocytic membrane was equal in both groups. The activity of Na-K-ATP-ase in the membrane of reconstituted erythrocytes increased with the action of calcium ions in the patients with hypertensive disease only half as much as in healthy persons.
与动脉血压正常者的红细胞相比,借助乙二胺四乙酸(EDTA)从高血压病患者的红细胞膜中去除的钙量更多。当使用等渗氯化镁时,两组从红细胞膜中去除的钙量相等。仅在高血压病患者中,重构红细胞膜中钠钾ATP酶的活性随钙离子作用的增加幅度仅为健康人的一半。