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炼油和石化行业产品及化学品的危险性和致癌特性。八、机动车燃料的健康影响:汽油的致癌性——科学进展。

Dangerous and cancer-causing properties of products and chemicals in the oil refining and petrochemical industry. VIII. Health effects of motor fuels: carcinogenicity of gasoline--scientific update.

作者信息

Mehlman M A

机构信息

ATSDR, Atlanta, Georgia 30333.

出版信息

Environ Res. 1992 Oct;59(1):238-49. doi: 10.1016/s0013-9351(05)80243-9.

DOI:10.1016/s0013-9351(05)80243-9
PMID:1425514
Abstract
  1. Significant increases in tumors of kidney, liver, and other tissues and organs following exposure to gasoline provide sufficient evidence of carcinogenicity. 2. Benzene, a significant component of gasoline, has been established without question as a human carcinogen by IARC, EPA, and WHO. 3. 1,3-Butadiene, a component of gasoline, is a powerful carcinogen in both animals and humans. 4. Sufficient evidence for the carcinogenicity of alkyl benzenes, very significant components of gasoline, has also been established. 5. Human epidemiologic studies show important increases in cancers of the kidney, stomach, brain, pancreas, prostate, lung, and skin as well as hematopoietic and lymphatic leukemias as a result of exposure to gasoline, its components, and its vapors. 6. Stage 2 controls are being implemented to reduce exposure of the human population to gasoline vapors.
摘要
  1. 接触汽油后,肾脏、肝脏及其他组织和器官的肿瘤显著增加,这为其致癌性提供了充分证据。2. 苯是汽油的重要成分,已被国际癌症研究机构(IARC)、美国环境保护局(EPA)和世界卫生组织(WHO)毫无争议地认定为人类致癌物。3. 1,3 - 丁二烯是汽油的一种成分,在动物和人类中都是一种强大的致癌物。4. 烷基苯是汽油的非常重要的成分,其致癌性也已有充分证据。5. 人类流行病学研究表明,接触汽油、其成分及其蒸气会导致肾脏、胃、脑、胰腺、前列腺、肺和皮肤的癌症以及造血和淋巴白血病显著增加。6. 目前正在实施第二阶段控制措施,以减少人群接触汽油蒸气的机会。

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