MARGHERITA S S, FRIEDMAN H
J Bacteriol. 1965 Feb;89(2):277-80. doi: 10.1128/jb.89.2.277-280.1965.
Margherita, S. S. (Temple University School of Medicine, Philadelphia, Pa.), and H. Friedmann. Induction of nonspecific resistance by endotoxin in unresponsive mice. J. Bacteriol. 89:277-280. 1965.-Serratia marcescens endotoxin was tested for protective effect in animals of varying immunological competence. A quantity of endotoxin capable of inducing resistance in mice to a standardized challenge of Diplococcus pneumoniae was equally effective in animals immunologically paralyzed with a high dose of homologous pneumococcal polysaccharide. Failure of the unresponsive state to influence the degree of resistance induced by endotoxin suggests that a specific humoral factor does not play a significant role in the nonspecific resistance.
玛格丽塔，S. S.（宾夕法尼亚州费城坦普尔大学医学院）和H. 弗里德曼。内毒素在无反应小鼠中诱导非特异性抵抗力。《细菌学杂志》89:277 - 280。1965年。——对粘质沙雷氏菌内毒素在不同免疫能力动物中的保护作用进行了测试。一定量能使小鼠对肺炎双球菌标准攻击产生抵抗力的内毒素，在被高剂量同源肺炎球菌多糖免疫麻痹的动物中同样有效。无反应状态未能影响内毒素诱导的抵抗程度，这表明特异性体液因子在非特异性抵抗中不起重要作用。
