[兔与人静脉注射后促性腺激素释放激素的尿排泄情况]
[Urinary excretion of LH-RH after intravenous injection in rabbit and man].
作者信息
Bourguignon J P, Leinartz-Dourcy C, Franchimont P
出版信息
C R Seances Soc Biol Fil. 1977;171(2):464-72.
PMID:142572
Abstract
The excretion of immunoreactive and radioactive material in urine was studied after intravenous injection of synthetic LH-RH in a rabbit and in a man. The LH-RH-like immunoreactive substance (LHRH-LIS) found in unextracted urine by radioimmunoassay was excreted within the same timelag and in the same proportions in the rabbit and in the human, but different from those of synthetic LH-RH, as shown by purifications on sephadex.
摘要
在给一只兔子和一名男子静脉注射合成促黄体激素释放激素（LH-RH）后，对尿液中免疫反应性和放射性物质的排泄情况进行了研究。通过放射免疫分析法在未提取的尿液中发现的促黄体激素释放激素样免疫反应性物质（LHRH-LIS），在兔子和人类体内以相同的时间间隔和相同的比例排泄，但如通过葡聚糖凝胶纯化所示，其排泄情况与合成LH-RH不同。
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