Saladié J M, Blasco F J
Department of Urology and Transplant Surgery, Universidad Autónoma de Barcelona, Spain.
Eur Urol. 1992;22(1):79-82. doi: 10.1159/000474727.
The development of an experimental model for ureteral autotransplantation without kidney transplantation, in an attempt to confirm viability of the ureter after denervation and total ischemia, is reported. Stages of the study and the experimental microsurgical technique used are discussed. Experiments were carried out in 30 Sprague-Dawley rats distributed in two experimental stages. The absence of histologic lesions was demonstrated by exeresis of the autotransplantated ureter and latter pathological study. Size, colour, renal consistency, ureteral peristalsis and the macroscopic appearance of the surgical piece were recorded. Histological examination confirmed macro- and microscopic normality of the autotransplanted ureteral segment.
本文报道了一种不进行肾移植的输尿管自体移植实验模型的开发，旨在确认去神经支配和完全缺血后输尿管的存活能力。讨论了研究阶段和所采用的实验显微手术技术。实验在30只Sprague-Dawley大鼠身上进行，分为两个实验阶段。通过切除自体移植的输尿管并进行后续病理研究，证实了无组织学病变。记录了手术部位的大小、颜色、肾脏质地、输尿管蠕动以及外观。组织学检查证实了自体移植输尿管段在宏观和微观上的正常状态。
