Hero M, Bird A C, Awadzi K
Onchocerciasis Chemotherapy Research Centre, Hohoe Hospital, Ghana.
Eye (Lond). 1992;6 ( Pt 1):93-6. doi: 10.1038/eye.1992.19.
Severe adverse systemic and ocular reactions have complicated the chemotherapy of onchocerciasis. A method for the quantification of ocular reactions to chemotherapy has been devised at the Onchocerciasis Chemotherapy Research Centre, at Hohoe, in Ghana. Symptoms, visual function, anterior segment inflammation and disease of the posterior segment are graded. The information is entered into a computerised database which allows reaction scores to be calculated both for individual patients, and for treatment groups. This system enables comparison of adverse ocular reactions to various new chemotherapeutic regimens.
严重的全身和眼部不良反应使盘尾丝虫病的化疗变得复杂。加纳霍霍的盘尾丝虫病化疗研究中心设计了一种量化化疗眼部反应的方法。对症状、视觉功能、前段炎症和后段疾病进行分级。这些信息被输入计算机化数据库，该数据库可以计算个体患者和治疗组的反应分数。该系统能够比较各种新化疗方案的眼部不良反应。
