Burk R O, Rohrschneider K, Noack H, Völcker H E
Universitäts-Augenklinik, Heidelberg, Federal Republic of Germany.
Graefes Arch Clin Exp Ophthalmol. 1992;230(6):552-60. doi: 10.1007/BF00181778.
To evaluate the effects of the presence of glaucomatous visual field defects and of intraocular pressure elevations on optic nerve head topography, we analyzed 148 left optic nerve heads of 148 patients using laser scanning tomography. The optic discs are classified according to computerized static perimetry and documented IOP readings: 101 discs show normal visual fields (36 normal discs, 22 ocular hypertensives, 28 normotensive glaucoma suspects and 15 ocular hypertensive glaucoma suspects), 47 discs (34 high-pressure glaucoma discs, 13 normal-tension glaucoma discs) demonstrate glaucomatous visual field damage. A two-way analysis of variance discloses significant differences (P < 0.01) between the groups of optic discs classified according to perimetry for most topometric parameters evaluated except for disc area. Classification according to documented IOP (cut off at 21 mmHg) results in larger disc areas in normotensive discs compared to hypertensive optic nerve heads in the study population. Results suggest that large discs may be susceptible to glaucomatous visual field damage at statistically normal IOP readings.
为评估青光眼性视野缺损和眼压升高对视乳头地形图的影响，我们使用激光扫描断层扫描技术分析了148例患者的148个左侧视乳头。根据计算机静态视野检查和记录的眼压读数对视盘进行分类：101个视盘显示视野正常（36个正常视盘、22个高眼压症患者、28个正常眼压性青光眼可疑患者和15个高眼压性青光眼可疑患者），47个视盘（34个高眼压性青光眼视盘、13个正常眼压性青光眼视盘）表现出青光眼性视野损害。双向方差分析显示，除视盘面积外，根据视野检查分类的视盘组之间，对于大多数评估的地形图参数存在显著差异（P < 0.01）。在研究人群中，根据记录的眼压（以21 mmHg为界）分类，正常眼压视盘的视盘面积比高眼压视乳头更大。结果表明，在统计学上正常的眼压读数下，大视盘可能易患青光眼性视野损害。
