Cheslyn-Curtis S, Gillams A R, Russell R C, Donald J J, Lake S P, Ainley C A, Hatfield A R, Lees W R
Pancreatobiliary Unit, Middlesex Hospital, London.
Gut. 1992 Sep;33(9):1253-9. doi: 10.1136/gut.33.9.1253.
Between January 1988 and December 1990, 283 patients with symptomatic gall stones were referred for non-operative treatment. After ultrasound scanning including a functional assessment, 220 (78%) patients were found to be suitable for percutaneous cholecystolithotomy. Of these, 113 underwent the procedure including 10 in whom extracorporeal shock-wave lithotripsy or methyl tert-butyl ether therapy had failed. Forty four patients underwent extracorporeal shockwave lithotripsy, methyl tert-butyl ether therapy or rotary lithotripsy, 46 chose laparoscopic cholecystectomy or minicholecystectomy and 27 declined treatment. Percutaneous cholecystolithotomy was successfully performed in 100 patients. Thirty four patients were a high operative risk and 14 presented with an acute complication of gall stone disease. Complications developed in 15 patients, all of whom were managed conservatively and most occurred during development of the technique. Outcome has been assessed clinically and by ultrasound scanning in 92 patients with a median follow up period of 14 months (six to 37 months). Seventy nine per cent were completely cured of their symptoms. Ninety three per cent of gall bladders were shown to be functioning and nine (9.8%) contained stones, although five of these are believed to have developed from residual fragments. Percutaneous cholecystolithotomy is a safe, non-operative treatment for symptomatic gall stones and enabled the patient to fully recover within two to three weeks; it has a definite role in the management of the elderly and high risk patient but its use for the treatment of other groups is likely to remain controversial.
1988年1月至1990年12月期间,283例有症状胆结石患者被转诊接受非手术治疗。在进行包括功能评估的超声扫描后,发现220例(78%)患者适合经皮胆囊碎石取石术。其中,113例接受了该手术,包括10例体外冲击波碎石术或甲基叔丁基醚疗法失败的患者。44例患者接受了体外冲击波碎石术、甲基叔丁基醚疗法或旋转碎石术,46例选择了腹腔镜胆囊切除术或小切口胆囊切除术,27例拒绝治疗。100例患者成功进行了经皮胆囊碎石取石术。34例患者手术风险高,14例出现胆结石疾病的急性并发症。15例患者出现并发症,均经保守治疗,大多数并发症发生在技术发展过程中。对92例患者进行了临床评估和超声扫描,中位随访期为14个月(6至37个月)。79%的患者症状完全治愈。93%的胆囊显示功能正常,9个(9.8%)胆囊含有结石,不过其中5个据信是由残留碎片形成的。经皮胆囊碎石取石术是一种治疗有症状胆结石的安全非手术方法,能使患者在两到三周内完全康复;它在老年和高危患者的治疗中具有明确作用,但在其他人群中的应用可能仍存在争议。