葡萄球菌毒素和链球菌毒素对类胸膜肺炎微生物的溶解作用

LYSIS OF PLEUROPNEUMONIA-LIKE ORGANISMS BY STAPHYLOCOCCAL AND STREPTOCOCCAL TOXINS.

作者信息

BERNHEIMER A W, DAVIDSON M

出版信息

Science. 1965 May 28;148(3674):1229-31. doi: 10.1126/science.148.3674.1229.

DOI:10.1126/science.148.3674.1229

Abstract

Six strains representing three species of Mycoplasma were examined for susceptibility to lysis by staphylococcal and streptococcal toxins. All were sensitive to staphylococcal alpha-toxin, two to streptolysin S, and three to streptolysin O. The results support the concept that the limiting membrane of pleuropneumonia-like organisms is basically similar to those of many other cell types and provide additional evidence for the participation of cholesterol in cytolysis induced by streptolysin O.

摘要

对代表三种支原体的六个菌株进行了检测，以确定它们对葡萄球菌和链球菌毒素裂解作用的敏感性。所有菌株均对葡萄球菌α毒素敏感，两个菌株对链球菌溶血素S敏感，三个菌株对链球菌溶血素O敏感。这些结果支持了这样一种概念，即类胸膜肺炎微生物的限制膜与许多其他细胞类型的限制膜基本相似，并为胆固醇参与链球菌溶血素O诱导的细胞溶解提供了额外证据。