BERNHEIMER A W, SCHWARTZ L L
J Bacteriol. 1965 May;89(5):1387-92. doi: 10.1128/jb.89.5.1387-1392.1965.
Bernheimer, Alan W. (New York University School of Medicine, New York, N.Y.), and Lois L. Schwartz. Lysis of bacterial protoplasts and spheroplasts by staphylococcal alpha-toxin and streptolysin S. J. Bacteriol. 89:1387-1392. 1965.-Protoplasts of Bacillus megaterium, Sarcina lutea, and Streptococcus pyogenes, and spheroplasts of Escherichia coli were lysed by staphylococcal alpha-toxin, whereas spheroplasts of Vibrio metschnikovii and V. comma were not. In the spectrum of its lytic action, streptolysin S qualitatively resembled staphylococcal alpha-toxin except for failure to lyse S. pyogenes protoplasts. In contrast to the two foregoing agents, streptolysin O did not lyse protoplasts and spheroplasts. The observations are interpreted in relation to similarities and differences in lipid composition of bacterial and mammalian cell membranes.
伯恩海默，艾伦·W.（纽约大学医学院，纽约，纽约州），以及洛伊斯·L.施瓦茨。葡萄球菌α毒素和链球菌溶血素S对细菌原生质体和球状体的裂解作用。《细菌学杂志》89:1387 - 1392。1965年。——巨大芽孢杆菌、藤黄八叠球菌和化脓性链球菌的原生质体，以及大肠杆菌的球状体可被葡萄球菌α毒素裂解，而梅契尼科夫弧菌和霍乱弧菌的球状体则不能。在其裂解作用谱方面，链球菌溶血素S在性质上类似于葡萄球菌α毒素，只是不能裂解化脓性链球菌原生质体。与上述两种试剂不同，链球菌溶血素O不能裂解原生质体和球状体。这些观察结果是根据细菌和哺乳动物细胞膜脂质组成的异同来解释的。
