Bernheimer A W
J Bacteriol. 1966 May;91(5):1677-80. doi: 10.1128/jb.91.5.1677-1680.1966.
Bernheimer, Alan W. (New York University School of Medicine, New York, N.Y.). Disruption of wall-less bacteria by streptococcal and staphylococcal toxins. J. Bacteriol. 91:1677-1680. 1966.-Earlier studies demonstrating that staphylococcal alpha-toxin and streptolysin S have the capacity to lyse protoplasts and spheroplasts of certain species of bacteria and Mycoplasma have been extended to encompass additional kinds of wall-less bacteria including L forms. It is suggested that sensitivity to staphylococcal alpha-toxin and streptolysin S may be explicable in terms of specific phospholipid composition of cell membranes, whereas sensitivity to streptolysin O is dependent upon the presence in cell membranes of cholesterol. The results suggest that streptolysin O might prove to be a useful reagent for differentiating L forms from parasitic pleuropneumonia-like organisms.
伯恩海默,艾伦·W.(纽约大学医学院,纽约州纽约市)。链球菌和葡萄球菌毒素对无壁细菌的破坏作用。《细菌学杂志》91:1677 - 1680。1966年。- 早期研究表明葡萄球菌α毒素和链球菌溶血素S能够裂解某些细菌和支原体物种的原生质体和球状体,现已扩展到包括L型菌在内的其他种类无壁细菌。有人提出,对葡萄球菌α毒素和链球菌溶血素S的敏感性可能可以根据细胞膜的特定磷脂组成来解释,而对链球菌溶血素O的敏感性则取决于细胞膜中胆固醇的存在。结果表明,链球菌溶血素O可能被证明是区分L型菌与寄生性胸膜肺炎样生物体的有用试剂。