与标准抗蛇毒血清相比，罗素蝰蛇毒类毒素抗蛇毒血清的中和效力。
Neutralization potency of Russell's viper venom toxoid antivenom, as compared with standard antivenom.
作者信息
Mandal M, Hati R N, Hati A K
机构信息
Department of Medicinal Entomology, Calcutta School of Tropical Medicine.
出版信息
Indian J Med Res. 1992 Aug;96:219-22.
Rabbits were immunized with gamma (gamma) irradiated Russell's viper venom toxoid, adsorbed to aluminium phosphate adjuvant. Antibody (raised against toxoid inoculation) titer was compared to a commercial antivenom on the basis of its ability to neutralize hemorrhagic, necrotic and lethal effects of viper venom. Toxoid immunization (on day 0, 15 and 30) produced antivenom which showed approximately one-third antilethal, half antihemorrhagic and antinecrotic titers as compared to those of the commercial hyperimmunized, concentrated horse antivenom.
用经γ射线辐照的罗素蝰蛇毒类毒素免疫兔子，该类毒素吸附于磷酸铝佐剂上。将（针对类毒素接种产生的）抗体效价与一种商业抗蛇毒血清进行比较，比较依据是其中和蝰蛇毒出血、坏死和致死作用的能力。类毒素免疫（在第0、15和30天进行）产生的抗蛇毒血清，与商业超免疫浓缩马抗蛇毒血清相比，其抗致死效价约为三分之一，抗出血和抗坏死效价约为一半。
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