Sulc J, Samánek M, Zapletal A
Kardiocentrum, University Hospital Motol, Prague, Czechoslovakia.
Int J Cardiol. 1992 Oct;37(1):15-21. doi: 10.1016/0167-5273(92)90127-o.
Lung volume, indices of lung elasticity and airway patency were measured in 74 patients, 9-21 yr old (15.0 +/- 2.5 yr) with atrial septal defect (secundum type) from 2-11 (5.1 +/- 2.5) yr after successful surgical correction. Clinical condition in all patients was classified as excellent. Heart surgery was performed at the age of 4-14.8 (9.9 +/- 3.0) yr. Lung function abnormalities were found in 35 (47.3%) patients. Lung recoil pressure was significantly increased in 24 (32.4%) patients. The mean value of lung recoil pressure at 100% of total lung capacity reached 123 +/- 31% of the predicted value (P < 0.0001). Specific static compliance was within normal limits. Specific airway conductance was significantly reduced in 13 (17.6%) patients. Maximum expiratory flow at 25% of vital capacity was significantly reduced in 4 (5.4%) patients. Static lung volumes did not differ from reference values. Since various abnormalities of lung function tests (most frequently the tests suggested increased lung stiffness and obstruction of larger airways) were revealed in almost half of the studied children and adolescents after successful surgery for atrial septal defect, we propose to carry out lung function tests routinely as another criterion of health conditions in these patients.
对74例年龄在9至21岁(平均15.0±2.5岁)的继发孔型房间隔缺损患者进行了肺容量、肺弹性指标和气道通畅性测量,这些患者在成功手术矫正后2至11年(平均5.1±2.5年)。所有患者的临床状况均被分类为良好。心脏手术在4至14.8岁(平均9.9±3.0岁)时进行。35例(47.3%)患者发现肺功能异常。24例(32.4%)患者的肺回缩压显著升高。在肺总量100%时肺回缩压的平均值达到预测值的123±31%(P<0.0001)。比静态顺应性在正常范围内。13例(17.6%)患者的比气道传导率显著降低。4例(5.4%)患者在肺活量25%时的最大呼气流量显著降低。静态肺容量与参考值无差异。由于在继发孔型房间隔缺损成功手术后,几乎一半的研究儿童和青少年出现了各种肺功能测试异常(最常见的是测试提示肺硬度增加和较大气道阻塞),我们建议将肺功能测试作为这些患者健康状况的另一标准进行常规检查。