Abecia E, Honrubia F M
Department of Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain.
Int Ophthalmol. 1992 Sep;16(4-5):239-42. doi: 10.1007/BF00917968.
Preliminary results of a larger investigation on correlation between Retinal Nerve Fiber Layer Defects (RNFL) and Automated Perimetry (AP) are presented. A group of ocular hypertensive patients was recruited and a cross-section, randomized study was carried out. The group was composed of 54 eyes from 28 patients; 15 men and 13 women, mean age 42.76 year, mean visual acuity 0.95 (Snellen cart) and mean visual defect expressed in diopters was +0.514 (from -2.5 to +5). A total of 17 (31.48%) refractive fields were pathologic according to our criteria, one from a normal RNFL and the others from nerve fiber defects. We observed 6 no reliable RNFL photographs, 18 normal, 11 slits, 6 wedge, 11 diffuse and 2 mixed defects. Comparing RNFL and AP, 53.33% of eyes with fiber defects had abnormal perimetries. The more evolutioned the defect, the larger percentage of abnormal visual fields were observed: 36.36% in slit defects, 66.66% in wedge, 54.55% in diffuse and 100% in mixed ones. Comparing location of defects with location of cluster of decreased sensibility points in visual field, a higher correlation in inferior than superior defects was found.
本文展示了一项关于视网膜神经纤维层缺损（RNFL）与自动视野计（AP）相关性的大型调查的初步结果。招募了一组高眼压患者，并进行了一项横断面随机研究。该组由28名患者的54只眼睛组成；其中15名男性和13名女性，平均年龄42.76岁，平均视力0.95（斯内伦视力表），以屈光度表示的平均视觉缺陷为+0.514（范围从-2.5至+5）。根据我们的标准，共有17个（31.48%）屈光视野为病理性，其中1个来自正常RNFL，其余来自神经纤维缺损。我们观察到6张RNFL照片不可靠，18张正常，11张裂隙状，6张楔形，11张弥漫性和2张混合性缺损。比较RNFL和AP，53.33%有纤维缺损的眼睛视野异常。缺损越严重，观察到的异常视野百分比越高：裂隙状缺损为36.36%，楔形为66.66%，弥漫性为54.55%，混合性为100%。比较缺损位置与视野中敏感度降低点簇的位置，发现下方缺损的相关性高于上方缺损。
