Prpic-Majic D, Pongracic J, Hrsak J, Pizent A
Institute for Medical Research and Occupational Health, University of Zagreb, Croatia.
Isr J Med Sci. 1992 Aug-Sep;28(8-9):548-56.
A follow-up study using biological and environmental monitoring was performed in a lead smelter community to assess the health risk of inhabitants and to establish how long it takes after the introduction of an effective emission control system to declare a lead-contaminated area safe for normal living. In specific population groups (mothers and children) biological indicators of lead exposure and lead effect on hemoglobin synthesis were determined 2 years before and 11 consecutive years after the installation of bag filters. At the same time lead was monitored in the airborne and deposited particulates, in household dust and in soil. The results clearly show that the process of normalization is rather slow. The difference in blood lead and erythrocyte delta-aminolevulinic acid dehydratase between the exposed and control groups, even 12 years after bag filters installation, was still remarkable. It appears that soil, contaminated with lead from past exposure, is a major source of increased lead absorption in a population for many years.
在一个铅冶炼厂社区开展了一项采用生物和环境监测的随访研究,以评估居民的健康风险,并确定在引入有效的排放控制系统后,需要多长时间才能宣布一个铅污染地区对正常生活来说是安全的。在特定人群组(母亲和儿童)中,在安装袋式过滤器之前2年以及之后连续11年,测定了铅暴露的生物指标以及铅对血红蛋白合成的影响。与此同时,对空气中和沉积颗粒物、家庭灰尘和土壤中的铅进行了监测。结果清楚地表明,恢复正常的过程相当缓慢。即使在安装袋式过滤器12年后,暴露组和对照组之间的血铅和红细胞δ-氨基乙酰丙酸脱水酶差异仍然显著。看来,过去暴露造成铅污染的土壤多年来一直是人群中铅吸收增加的主要来源。