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患有儿童精神疾病的双胞胎与单胞胎的比较:一项项目表研究。

A comparison of twins and singletons with child psychiatric disorders: an Item Sheet study.

作者信息

Simonoff E

机构信息

Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London, U.K.

出版信息

J Child Psychol Psychiatry. 1992 Nov;33(8):1319-32. doi: 10.1111/j.1469-7610.1992.tb00952.x.

Abstract

An important assumption underlying the twin method of comparing MZ and DZ twins is that results from twin samples can be generalized to the larger singleton population. This study uses Item Sheet data on child psychiatric patients to compare twins and singletons on demographic, diagnostic and symptomatic variables. Although little difference was found between the two groups, conduct disorders were significantly over-represented in the twin population. The significance of this finding is discussed. This study lends overall support for the use of the twin method in child psychiatric samples.

摘要

比较同卵双胞胎(MZ)和异卵双胞胎(DZ)的双胞胎研究方法所基于的一个重要假设是,双胞胎样本的研究结果可以推广到更大的单胎人群中。本研究使用儿童精神病患者的项目表数据,比较双胞胎和单胎在人口统计学、诊断和症状变量方面的情况。虽然两组之间差异不大,但品行障碍在双胞胎人群中的比例显著过高。本文讨论了这一发现的意义。本研究为在儿童精神病样本中使用双胞胎研究方法提供了总体支持。

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