Gonzalez E, Gange R W, Momtaz K T
Harvard Medical School, Massachusetts General Hospital, Boston 02114.
J Am Acad Dermatol. 1992 Aug;27(2 Pt 1):220-6. doi: 10.1016/0190-9622(92)70174-e.
This study was undertaken to evaluate the effectiveness and safety of the 577 nm pulsed dye laser in the treatment of various vascular lesions of the face.
Our purpose was to make observations on the effects of different variables that could affect response.
Ninety-two adults with telangiectases of the face were sequentially selected for treatment according to a protocol previously established. Evaluation consisted of visual inspection by two investigators, and before and after photographs at 2-months intervals. A few patients with other vascular lesions were also treated and reported.
Ninety-one percent of the patients (84 of 92) showed good to excellent response after a single treatment. Recurrence occurred in 2%. Atrophy of the skin occurred in 2%. Venous lakes, pyogenic granulomas, and mucosal vascular malformations showed significant improvement.
The 577 nm pulsed dye laser is effective and safe for vascular lesions of the face.
本研究旨在评估577纳米脉冲染料激光治疗面部各种血管病变的有效性和安全性。
我们的目的是观察不同变量对治疗反应的影响。
根据先前制定的方案，依次选择92例面部毛细血管扩张的成年人进行治疗。评估包括两名研究者的目视检查，以及每隔2个月拍摄的治疗前后照片。少数患有其他血管病变的患者也接受了治疗并进行了报告。
91%的患者（92例中的84例）单次治疗后显示出良好至极佳的反应。复发率为2%。皮肤萎缩发生率为2%。静脉湖、化脓性肉芽肿和黏膜血管畸形有显著改善。
577纳米脉冲染料激光治疗面部血管病变有效且安全。
