González S, Vibhagool C, Falo L D, Momtaz K T, Grevelink J, González E
Department of Dermatology, Massachusetts General Hospital, Boston, MA 02114, USA.
J Am Acad Dermatol. 1996 Sep;35(3 Pt 1):428-31. doi: 10.1016/s0190-9622(96)90610-6.
Current therapeutic alternatives for pyogenic granulomas include surgical excision, electrodesiccation and curettage, cryotherapy, and ablation with CO2 or continuous-wave vascular lasers.
Our purpose was to investigate the use of the 585 nm flashlamp-pumped pulsed dye laser (585 nm PDL) for the treatment of pyogenic granulomas in terms of efficacy, advantages in technique, and side effects.
Eighteen patients with symptomatic pyogenic granulomas in a variety of locations were treated with the 585 nm PDL and examined.
Sixteen of 18 treated patients demonstrated both symptomatic and clinical clearing of the lesions with excellent cosmetic results after treatment. The two patients who dropped out after one to two 585 nm PDL treatments were eventually treated successfully with electrodesiccation and curettage. No postoperative complications and no persistent pigmentary changes or scarring were observed. The procedure required no anesthesia, and postoperative care was limited to the application of a topical antibiotic ointment.
Our experience suggests that treatment of pyogenic granulomas with the 585 nm PDL is a safe, effective, and reasonable alternative to conventional therapy.
目前治疗化脓性肉芽肿的方法包括手术切除、电干燥刮除术、冷冻疗法以及用二氧化碳或连续波血管激光进行消融。
我们的目的是从疗效、技术优势和副作用方面研究585纳米闪光灯泵浦脉冲染料激光（585nm PDL）治疗化脓性肉芽肿的应用。
对18例不同部位有症状的化脓性肉芽肿患者用585nm PDL进行治疗并检查。
18例接受治疗的患者中有16例病变症状和临床表现均消失，治疗后美容效果极佳。在接受一至两次585nm PDL治疗后退出的两名患者最终通过电干燥刮除术成功治愈。未观察到术后并发症以及持续性色素沉着改变或瘢痕形成。该治疗过程无需麻醉，术后护理仅限于局部应用抗生素软膏。
我们经验表明，用585nm PDL治疗化脓性肉芽肿是一种安全、有效且合理的传统治疗替代方法。
