Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea.
J Cosmet Dermatol. 2019 Jun;18(3):783-787. doi: 10.1111/jocd.12692. Epub 2018 Jul 4.
A 595-nm pulsed dye laser (PDL) and the fractional 532-nm potassium titanyl phosphate (KTP) laser have also been demonstrated to be effective for facial telangiectasias.
To compare the clinical therapeutic effects of a fractional 532-nm KTP laser with those of a 595-nm pulsed dye laser (PDL) for treating facial erythematous skin lesions.
Twenty healthy adults with facial erythematous skin lesions were treated using a fractional 532-nm KTP laser on one side of the face and a 595-nm PDL on the other cheek. Three treatments were administered at 4-week intervals. The degree of improvement in facial telangiectasias was evaluated by colorimeter analysis, a physician's assessment using clinical photographs, and the subject's self-assessment.
In the physician's assessment with clinical photography, a significant improvement was observed from baseline to posttreatment in both groups. As measured by a colorimeter, the a* value decreased from 16.23 (±2.81) to 12.22 (±2.75) in the 595-nm PDL group and from 16.02 (±2.93) to 12.77 (±2.77) in the fractional 532-nm KTP laser group. The a* value showed a significant reduction in both groups (P < .0001). There was no significant difference in efficacy between the two groups. In the subjective self-assessment, scores improved by 1.68 (±0.95) in the fractional 532-nm KTP laser group and by 1.78 (±0.92) in the 595-nm PDL group.
A fractional 532-nm KTP laser is a valid option for the treatment of facial erythematous skin lesions with telangiectasia.
595nm 脉冲染料激光（PDL）和 532nm 倍频铷钛酸钾（KTP）激光也已被证明对治疗面部毛细血管扩张有效。
比较 532nm 倍频 KTP 激光与 595nm 脉冲染料激光（PDL）治疗面部红斑性皮损的临床疗效。
20 例面部红斑性皮损患者，一侧面部采用 532nm 倍频 KTP 激光治疗，对侧采用 595nm PDL 治疗，每 4 周治疗 1 次，共治疗 3 次。采用色差仪分析、医生临床照片评估和患者自评评估面部毛细血管扩张改善程度。
在医生临床照片评估中，两组患者治疗后均较基线有显著改善。经色差仪测量，595nm PDL 组 a值由治疗前的 16.23（±2.81）降至治疗后的 12.22（±2.75），532nm 倍频 KTP 激光组由 16.02（±2.93）降至 12.77（±2.77），两组患者的 a值均显著降低（P<.0001）。两组间疗效无显著差异。在患者自评中，532nm 倍频 KTP 激光组评分提高 1.68（±0.95），595nm PDL 组评分提高 1.78（±0.92）。
532nm 倍频 KTP 激光是治疗面部毛细血管扩张性红斑性皮损的有效选择。
