Neuhold A, Hofmann S, Engel A, Leder K, Kramer J, Haller J, Plenk H
Institute for Diagnostic Imaging, Rudolfinerhaus Hospital, Vienna, Austria.
J Comput Assist Tomogr. 1992 Nov-Dec;16(6):951-5. doi: 10.1097/00004728-199211000-00023.
Magnetic resonance imaging is an extremely sensitive technique for evaluation of bone marrow changes at an early stage of avascular necrosis (AVN) of the hip. We therefore examined 11 painful hips whose clinical symptoms led us to suspect idiopathic AVN. The radiographs of all of these either were normal or demonstrated a minimal decrease in radiodensity. Magnetic resonance demonstrated diffuse signal loss of the bone marrow at short TR/TE images of the femoral head in all hips, with various extensions in the head, neck, and intertrochanteric area. These regions turned iso- to hyperintense on long TR/TE images compatible with bone marrow edema (BME). Focal abnormalities characteristic for AVN were not seen in any of the cases. Radionuclide studies performed in six cases were positive. All patients underwent core decompression treatment. Hydrostatic bone marrow pressure measurement and intraosseous venography were positive in five cases when measured. Histology available in eight cases confirmed the presence of BME. Furthermore, the bone changes corresponded to those of early AVN. Follow-up examinations after core decompression with MR showed normal signal intensity in all cases. Magnetic resonance represents a viable diagnostic tool for BME and can monitor the therapeutic success of core decompression. Whether BME of the femoral head constitutes a distinct transient syndrome or represents an early form of AVN is controversial at present. Our findings support those who believe that BME may represent an initial stage of idiopathic AVN.
磁共振成像(MRI)是评估髋关节缺血性坏死(AVN)早期骨髓变化的一项极其敏感的技术。因此,我们对11例有疼痛症状的髋关节进行了检查,这些临床症状使我们怀疑为特发性AVN。所有这些患者的X线片要么正常,要么显示骨密度略有降低。MRI显示,所有髋关节股骨头的短TR/TE图像上骨髓均呈弥漫性信号缺失,在股骨头、股骨颈和转子间区域有不同程度的延伸。在长TR/TE图像上,这些区域变为等信号至高信号,符合骨髓水肿(BME)表现。所有病例均未见到AVN特有的局灶性异常。6例患者进行的放射性核素检查呈阳性。所有患者均接受了髓芯减压治疗。5例患者在测量时,流体静力骨髓压力测量和骨内静脉造影呈阳性。8例患者的组织学检查证实存在BME。此外,骨改变与早期AVN相符。髓芯减压后用MRI进行的随访检查显示,所有病例信号强度均正常。MRI是诊断BME的一种可行工具,并且可以监测髓芯减压的治疗效果。目前,股骨头的BME是一种独特的短暂综合征还是AVN的早期形式存在争议。我们的研究结果支持那些认为BME可能代表特发性AVN初始阶段的观点。