WILSON T S, STUART R D
Can Med Assoc J. 1965 Jul 3;93(1):8-16.
Coagulase-negative Staphylococcus albus was considered to be the causal agent in 53 (4.4%) of 1200 wound infections investigated in a large general hospital over the eight-year period 1957-1964. There was clinical evidence of morbidity in these patients, with fever, but the infection cleared spontaneously, usually in a week or two, and antibiotics were unnecessary.Of much greater importance was the finding of this organism in blood cultures on repeated occasions, with associated clinical septicemia. Twelve patients were so affected, of whom six died, a mortality rate of 50%. Such data emphasize the tragic mistake of dismissing the report of Staph. albus in a blood culture as "only a contaminant", and of failure to recognize that the organism can cause serious disease. This is particularly true in poor-risk patients, and in those who have undergone cardiac surgery.
在1957年至1964年的八年期间,一家大型综合医院对1200例伤口感染进行了调查,其中53例(4.4%)的病因被认为是白色凝固酶阴性葡萄球菌。这些患者有发热等发病的临床证据,但感染通常在一两周内自行清除,无需使用抗生素。更重要的是,多次在血培养中发现这种微生物,并伴有临床败血症。12名患者受到影响,其中6人死亡,死亡率为50%。这些数据强调了将血培养中白色葡萄球菌的报告视为“仅是污染物”而不予理会,以及未能认识到该微生物可导致严重疾病的悲剧性错误。在高危患者以及接受心脏手术的患者中尤其如此。