Dencker S J
Proc R Soc Med. 1976;69 suppl 1(Suppl 1):32-4. doi: 10.1177/00359157760690S108.
More than 300 patients have been observed during treatment with either flupenthixol, haloperidol, fluphenazine enanthate or perphenazine enanthate in high doses, whilst suffering from severe mental disease, usually of psychotic nature. Used correctly, high-dose treatment gives a rapid control of psychotic symptoms, an earlier discharge from the ward, and (when using long-acting neuroleptics) pharmacological control even during a follow up period. This means a social availability gain of 30-50%. We have not seen any severe somatic effects except those of parkinsonian type which can be treated successfully by the well trained psychiatrist and a skilled staff.
超过300名患有严重精神疾病（通常为精神病性质）的患者在接受高剂量氟哌噻吨、氟哌啶醇、庚酸氟奋乃静或庚酸奋乃静治疗期间接受了观察。正确使用高剂量治疗可迅速控制精神病症状，使患者更早出院，并且（在使用长效抗精神病药物时）即使在随访期间也能实现药理控制。这意味着社会可及性提高了30%至50%。除了帕金森氏症类型的症状外，我们没有看到任何严重的躯体影响，而训练有素的精神科医生和熟练的工作人员可以成功治疗这些症状。
