Nukiwa T, Seyama K, Hanasato N, Hasunuma K, Kira S
Respiratory Medicine, Juntendo University.
Nihon Rinsho. 1992 Sep;50(9):2166-72.
Alveolar hypoventilation due to the chronic obstruction of the airway such as pulmonary emphysema, or severe restrictive dysfunction due to sequela of pulmonary tuberculosis causes chronic hypercapnia (chronic respiratory acidosis). Ninety-five percentile of significance band of chronic and acute hypercapnia of both experimental and clinical setting is introduced in the graphic display of the acid-base balance. On acute exacerbation of these disorders, examination of arterial blood gas in series are usually plotted along the significance band of hypercapnia. With clinical improvement, the plot will gradually drop down to the chronic stable area of the band. Although cases with metabolic disorders complicate the interpretation, evaluation of the acid-base status using the graphic display will be of help at bedside assessment.
诸如肺气肿等气道慢性阻塞引起的肺泡通气不足，或肺结核后遗症导致的严重限制性功能障碍，可引起慢性高碳酸血症（慢性呼吸性酸中毒）。在酸碱平衡的图形显示中引入了实验和临床环境下慢性和急性高碳酸血症95%置信区间。在这些疾病急性加重时，系列动脉血气检查结果通常沿高碳酸血症的置信区间绘制。随着临床症状改善，该曲线将逐渐下降至该区间的慢性稳定区域。尽管合并代谢紊乱的病例会使解读变得复杂，但利用图形显示评估酸碱状态将有助于床边评估。
