Yamamoto S, Morita C, Tsuchiya K
Miyazaki Prefectural Institute for Public Health and Environment.
Jpn J Med Sci Biol. 1992 Apr;45(2):81-6. doi: 10.7883/yoken1952.45.81.
A spotted fever group rickettsia was isolated from Apodemus mice captured near the site where a person had been infected in Miyazaki Prefecture. Antigenic characteristics of the isolate designated as strain TO-1 were compared with those of Rickettsia japonica (strain YH) and Rickettsia montana (ATCC VR611) by the indirect fluorescent antibody test with 14 serum specimens obtained from Apodemus speciosus, immune rat antisera against the strains TO-1 and YH, and three patients' sera. The titers of these sera measured with strain TO-1 were identical to those with strain YH, suggesting the antigenic similarity between these two organisms. It was also suggested that Apodemus speciosus is likely to be an important vertebrate host for a spotted fever group rickettsia in Japan.
从宫崎县一名感染者所在地附近捕获的姬鼠中分离出一株斑点热群立克次体。通过间接荧光抗体试验,用从日本姬鼠获得的14份血清标本、针对TO-1株和YH株的免疫大鼠抗血清以及3份患者血清,比较了命名为TO-1株的分离株与日本立克次体(YH株)和蒙大拿立克次体(ATCC VR611)的抗原特性。这些血清与TO-1株测定的效价与与YH株测定的效价相同,表明这两种微生物之间存在抗原相似性。还表明,日本姬鼠很可能是日本斑点热群立克次体的重要脊椎动物宿主。