Hoshina K, Itogawa H, Itagaki A, Gomyoda M, Uchida T
Shimane Prefectual Institute of Pablic Health and Environmental Science.
Kansenshogaku Zasshi. 1995 May;69(5):524-31. doi: 10.11150/kansenshogakuzasshi1970.69.524.
We carried out a survey for the prevalence of antibodies to the spotted fever group (SFG) rickettsia in vertebrates such as dogs, cattle, deer, and mice in Shimane Prefecture. Rickettsia japonica was employed as antigen in indirect immunofluorescence (IF) tests. The experiment for natural infections using decoy animals was performed in the field of the endemic area. 1. Among 115 street dogs, 18.3% possessed the antibodies against SFG rickettsia, while all of the 8 hunting dogs had the antibodies. 2. Among 234 cattle tested, 17.9% possessed the antibodies. IF titers were 1:40 to 1:160 (mean 1:68). 3. Among 69 wild deer, 92.7% possessed the antibodies ranging between 1:40 and 1:640, which showed the highest IF titers (mean 1:89) among those of the examined vertebrates. 4. The incidence of the antibodies in Apodemus speciosus, Apodemus argenteus and Eothenomys smithi smithi mice were 16.5, 4.3 and 0%, respectively. The incidence of the antibodies against SFG rickettsia in mice captured in the endemic area was significantly higher (22.8%) than that in non-endemicarea (10.4%). Difference in the incidence of antibody-positive mice was also observed within the endemic area. Therefore, we concluded that the infection of mice was restricted to a limited area. 5. No significant rise in IF titers was observed in decoy animals that had been infested with ticks in the endemic area.
我们对岛根县的犬、牛、鹿和小鼠等脊椎动物中斑点热群（SFG）立克次体抗体的流行情况进行了调查。在间接免疫荧光（IF）试验中使用日本立克次体作为抗原。在疫区现场用诱饵动物进行自然感染实验。1. 在115只流浪狗中，18.3%的狗拥有抗SFG立克次体抗体，而所有8只猎犬都有抗体。2. 在234头接受检测的牛中，17.9%的牛拥有抗体。IF滴度为1:40至1:160（平均1:68）。3. 在69只野生鹿中，92.7%的鹿拥有1:40至1:640之间的抗体，这是所检测的脊椎动物中IF滴度最高的（平均1:89）。4. 大林姬鼠、银姬鼠和中华姬鼠的抗体发生率分别为16.5%、4.3%和0%。在疫区捕获的小鼠中，抗SFG立克次体抗体的发生率（22.8%）显著高于非疫区（10.4%）。在疫区内部也观察到抗体阳性小鼠发生率的差异。因此，我们得出结论，小鼠的感染局限于有限的区域。5. 在疫区被蜱虫叮咬的诱饵动物中，未观察到IF滴度有显著升高。
