Maeta H, Imawaki S, Shiraishi Y, Komoda T, Tanaka S, Aibiki M
First Department of Surgery, Kagawa Medical School.
Kyobu Geka. 1992 Oct;45(11):979-84.
During the past 7 years, 15 patients with acute pulmonary embolism (APE) were treated at Kagawa Medical School and 10 patients were survived. Nine patients had an embolus in a right or left pulmonary trunk (group A) and 6 patients were peripheral APE (group B). In group A abnormal findings in a chest x-ray film and an electrocardiogram were observed in many patients, but in group B these findings were slight. In group A a shock was observed in 89% and cardiac arrest in 4 patients, although in group B neither shock nor death were observed. Marked hypoxia with hypocapnia was observed in 8 patients in group A and only in 2 in group B. All patients in group B were recovered by medical therapy. In group A, however, only 3 patients were recovered by medical therapy. Two patients in group A were performed pulmonary embolectomy (PER), but one of them, who had been in nonreversible shock, died. We conclude that the patient who had marked hypoxia (PO2 less than or equal to 50 mmHg) with hypocapnia (PCO2 less than or equal to 35 mmHg) early at an attack should be taken a pulmonary angiography, and when a large embolus is found out in the proximal pulmonary artery, the PER should be performed as soon as possible.
在过去7年中,香川医科大学收治了15例急性肺栓塞(APE)患者,其中10例存活。9例患者的栓子位于右或左肺动脉主干(A组),6例为外周性APE(B组)。A组中许多患者胸部X线片和心电图有异常表现,而B组这些表现较轻。A组中89%的患者出现休克,4例发生心脏骤停,而B组既未观察到休克也未观察到死亡。A组8例患者出现明显低氧血症伴低碳酸血症,B组仅2例。B组所有患者经药物治疗后康复。然而,A组中仅3例患者经药物治疗后康复。A组2例患者接受了肺动脉血栓切除术(PER),但其中1例处于不可逆休克状态,死亡。我们得出结论,对于发病早期即出现明显低氧血症(PO2≤50 mmHg)伴低碳酸血症(PCO2≤35 mmHg)的患者,应进行肺动脉造影,当在近端肺动脉发现大的栓子时,应尽快进行PER。