Medvedenko A F, Taranenko L D, Andrienko I B, Medvedenko A A
Klin Med (Mosk). 1992 May-Jun;70(5-6):17-9.
A therapeutic response was analyzed in 536 patients with acute destructive pancreatitis complicated by pancreatogenic enzymatic peritonitis. All the patients had the syndrome of endogenic intoxication and underwent intensive resuscitation with protease inhibitors, cytostatic agents, antibacterial, desensitization and detoxication treatment. If indicated, the patients with pronounced endogenic intoxication were subjected to forced diuresis, abdominal laparoscopic drainage and intraperitoneal dialysis, drainage of the thoracic lymphatic duct, hemosorption. Routine surgical intervention was performed. Up to 11% fell the general lethality due to a differentiated therapeutic approach.
对536例急性坏死性胰腺炎合并胰源性酶性腹膜炎患者的治疗反应进行了分析。所有患者均有内源性中毒综合征，并接受了蛋白酶抑制剂、细胞抑制剂、抗菌、脱敏和解毒治疗等强化复苏措施。如有指征，对有明显内源性中毒的患者进行强制利尿、腹部腹腔镜引流和腹膜透析、胸导管引流、血液吸附。进行了常规手术干预。由于采用了差异化的治疗方法，总体死亡率降至11%。
