Kulazhenkov S A, Anisimov M A, Fëdorov V N, Kuznetsov E V
Khirurgiia (Mosk). 1994 Jan(1):6-10.
The authors analysed 373 patients with acute pancreatitis which developed after operations on the organs of the pancreatoduodenal zone. Acute postoperative pancreatitis developed in 17.15% of cases after operations on the biliary tract, in 26.8% after resection of the stomach for ulcer, and in 51.47% of cases after resection of the stomach for carcinoma. A comparative evaluation of various methods for the prevention and treatment of acute postoperative pancreatitis (APP) is given, with appraisal of the traditional therapy (154 patients) without the use of protease inhibitors, and various methods of administration of protease inhibitors (135 patients) and cytostatics (84 patients). The mortality rate in progressive forms of APP was 25.2%, mortality being highest (30.4%) in treatment by the traditional methods including protease inhibitors and lowest in inclusion of cytostatics in the complex of therapeutic measures (7.1%).
作者分析了373例在胰十二指肠区器官手术后发生急性胰腺炎的患者。术后急性胰腺炎在胆道手术后的发生率为17.15%，胃溃疡胃切除术后为26.8%，胃癌胃切除术后为51.47%。文中对预防和治疗术后急性胰腺炎（APP）的各种方法进行了比较评估，评估了未使用蛋白酶抑制剂的传统疗法（154例患者）、蛋白酶抑制剂的各种给药方法（135例患者）和细胞抑制剂（84例患者）。进展型APP的死亡率为25.2%，其中采用包括蛋白酶抑制剂在内的传统方法治疗时死亡率最高（30.4%），而在治疗措施组合中加入细胞抑制剂时死亡率最低（7.1%）。
