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[精神药理学对雪貂(Putorius furo L.)捕食行为的影响(作者译)]

[Psychopharmacological influence on the prey catching behavior of ferrets (Putorius furo L.) (author's transl)].

作者信息

Schmidt W, Apfelbach R

出版信息

Psychopharmacology (Berl). 1977 Jan 31;51(2):147-52. doi: 10.1007/BF00431731.

DOI:10.1007/BF00431731
PMID:14351
Abstract

The prey-catching behavior of ferrets (Putorius furo L.) consists mainly of instinctive behavior patterns, which can be elicited only through their releaser. Then they are performed stereotypically. To get information concerning the central background and the hierarchical structure of this behavior the neuroleptics Haloperidol (0.14 mg/kg), Clozapine (10 mg/kg) and Chlorpromazine (4 mg/kg) were injected i.m. under controlled conditions. In a conditioning experiment the reactivity of the animals was examined. This conditioned reaction was strongly decreased by the drugs. The reaction to the natural stimulus the prey was changed, but not suppressed. The modification of the predatory behavior was manifedsted in an "improvement" of orientation reactions when pursuing the prey and in a better placement of bites. This effect, most evident with Haloperidol, is possibly due to the specific neuroleptic component of the substances. A delay in approaching the prey, or even the total suppression of the prey-catching behavior is suggested to be due to a sedative component which was most obvious in some experiments with Clozapine. On the other hand, there are behavioral elements like the use of paws which are not effected by the neuroleptics. From these and other observations, it is concluded, that the predatory behavior of the ferret has a hierarchically organisated structure. Further it is suggested that some functional connected parts of the behavior have distinct central representation, for they are not influenced in the same way by these drugs.

摘要

雪貂(水貂属黑足鼬)的捕食行为主要由本能行为模式组成,这些行为模式只能通过其释放者引发,然后刻板地执行。为了获取有关这种行为的中枢背景和层次结构的信息,在受控条件下肌肉注射了抗精神病药物氟哌啶醇(0.14毫克/千克)、氯氮平(10毫克/千克)和氯丙嗪(4毫克/千克)。在一项条件反射实验中,检测了动物的反应性。这些药物使这种条件反应大幅降低。对猎物这种自然刺激的反应发生了变化,但并未被抑制。捕食行为的改变表现为追捕猎物时定向反应的“改善”以及咬击位置更佳。这种效应在氟哌啶醇作用下最为明显,可能归因于这些物质的特定抗精神病成分。接近猎物的延迟,甚至捕食行为的完全抑制,被认为是由于镇静成分导致的,这在一些氯氮平实验中最为明显。另一方面,像使用爪子这样的行为元素不受抗精神病药物影响。从这些及其他观察结果得出结论,雪貂的捕食行为具有层次组织结构。此外,有人提出该行为的一些功能相关部分具有不同的中枢表征,因为它们受这些药物的影响方式不同。

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引用本文的文献

1
Involvement of dopaminergic neurotransmission in the control of goal-directed movements.多巴胺能神经传递在目标导向运动控制中的作用。
Psychopharmacology (Berl). 1983;80(4):360-4. doi: 10.1007/BF00432121.
2
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Psychopharmacology (Berl). 1979 Sep;64(3):355-9. doi: 10.1007/BF00427524.
3
Instinctive predatory behavior of the ferret (Putorius putorius furo L.) modified by chlordiazepoxide hydrochloride (Librium).

本文引用的文献

1
The quantitative effect of visual and tactile stimuli on the prey-catching behaviour of ferrets (Putorius furo L.).视觉和触觉刺激对雪貂(Putorius furo L.)捕食行为的定量影响。
Behav Processes. 1977 Jun;2(2):187-200. doi: 10.1016/0376-6357(77)90020-1.
2
[Pharmacology of catatonigenic drugs. 2. Elimination of the N. caudatus and the catatonigenic effects of neuroleptics].
Arzneimittelforschung. 1971 Mar;21(3):386-90.
3
Effects of drugs on the mouse-killing (muricide) test and its relationship to amygdaloid function.
Int J Neuropharmacol. 1966 Nov;5(6):405-11. doi: 10.1016/0028-3908(66)90005-0.
盐酸氯氮卓(利眠宁)对雪貂(白鼬指名亚种)本能捕食行为的影响
Psychopharmacology (Berl). 1978 Oct 31;59(2):179-82. doi: 10.1007/BF00427754.