Zakharova N F, Iakubovich V Ia, Ganushkina L A, Chunina L M
Med Parazitol (Mosk). 1992 Jul-Aug(4):22-6.
Making use of a model pair Aedes aegypti--Plasmodium gallinaceum, the authors assess the susceptibility of mosquito female survivors to malaria agent after treatment of larvae with various bioactive substances. Eight binary combinations of 6 preparations have been tried: dimilin and uvemon, insect development regulators; fundosol and copper sulfate, fungicides; phytobacteriomicin (PBM), a larvicidal antibiotic; bactoculicide, a bacterial agent. Combinations of PBM with compounds differing by their mechanisms of action were found to inhibit the specific effect of PBM on the vector, PBM specific effect consisting in depression of mosquito susceptibility to P. gallinaceum. PBM combinations with some agents may alter other parameters of the vector potential: combinations of copper sulfate or uvemon with low concentrations of PBM potentiated the larvicidal effect, and PBM mixtures with fungicides reduces the activity of female attacks.
利用埃及伊蚊-鸡疟原虫这一模型对，作者评估了在用各种生物活性物质处理幼虫后，存活的雌蚊对疟原虫病原体的易感性。尝试了6种制剂的8种二元组合：灭幼脲和优灭磷，昆虫发育调节剂；丰索磷和硫酸铜，杀菌剂；植物杀菌素（PBM），一种杀幼虫抗生素；细菌杀虫剂，一种细菌制剂。发现PBM与作用机制不同的化合物的组合会抑制PBM对病媒的特定作用，PBM的特定作用在于降低蚊子对鸡疟原虫的易感性。PBM与某些药剂的组合可能会改变病媒潜力的其他参数：硫酸铜或优灭磷与低浓度PBM的组合增强了杀幼虫效果，而PBM与杀菌剂的混合物降低了雌蚊叮咬的活性。
